Sabrina Paganoni, MD, PhD, is an Associate Professor of PM&R at Harvard Medical School / Spaulding Rehabilitation Hospital. She is the Co-Director of the Neurological Research Institute at the Massachusetts General Hospital,  the Robert H. Brown, Jr., PhilD, MD Endowed Chair in Neurology, and a member of the National Academy of Medicine. Her research focuses on clinical trials and therapy development for ALS. She is the Principal Investigator of several ALS clinical trials and has pioneered novel trial designs and partnership models to innovate the way investigational products are tested in ALS. She is the co-PI of the HEALEY ALS Platform Trial and is leading multi-center expanded access programs. She is working with other Harvard researchers on developing new assistive technology and care models for people with ALS and other forms of Motor Neuron Disease. Her research has been funded by the NIH, non-profits, and industry; she published more than 170 peer-reviewed manuscripts and received several awards for her work including the 2021 Top 10 Clinical Research Achievement Award.